Hektoen International

A Journal of Medical Humanities

Tag: Yellow Fever

  • Infectious diseases in the Civil War

    Lloyd Klein San Francisco, California, United States The main cause of death during the American Civil War was not battle injury but disease. About two-thirds of the 620,000 deaths of Civil War soldiers were caused by disease, including 63% of Union fatalities. Only 19% of Union soldiers died on the battlefield and 12% later succumbed to…

  • Death, disease, and discrimination during the construction of the Panama Canal (1904–1914)

    Enrique Chaves-CarballoOverland Park, Kansas, United States Theodore Roosevelt, Jr. (1858–1919) President Theodore Roosevelt envisioned an interoceanic canal as indispensable for American “dominance at the seas.”1 An isthmian canal would facilitate rapid deployment of U.S. Navy ships from Atlantic to Pacific Oceans, bypassing the arduous 2,000-mile trip around the tip of South America. However, construction of…

  • The history of quarantine and contact tracing as surveillance strategies

    Mariella ScerriVictor GrechMalta Quarantine, from the Italian quaranta, meaning forty, is a centuries-old public health measure instituted to control the spread of infectious diseases by mandating isolation, sanitary cordons, and other mitigation measures.1 Though essential in preventing the spread of disease, such measures have often been controversial, as they raised “political, ethical, and socioeconomic issues…

  • Oswaldo Cruz and the eradication of infectious diseases in Brazil

    Robert PerlmanChicago, Illinois, United States In 1899, an epidemic of bubonic plague caused a crisis in the Brazilian port city of Santos. Ship captains were angry that their boats had to remain in quarantine and so denied that the disease was plague. They and others argued that this new disease was not as deadly as…

  • George Crile Sr., founder of the Cleveland Clinic

    Early days George Crile was an exceptional man, a skilled surgeon who lived at a time when American medicine was emerging from its horse and buggy period and was embracing the principles of aseptic surgery and scientific medicine. Always full of new ideas, he was first to carry out a human-to-human blood transfusion. He made…

  • Origin of yellow fever

    Enrique Chaves-Carballo Kansas City, Kansas, United States The origin of yellow fever has been a controversial subject since the disease appeared in the New World. William C. Gorgas, who was responsible for the sanitation of Cuba and Panama, believed that yellow fever originated in Panama.1 Henry R. Carter, from the U.S. Marine Hospital Service and director…

  • Carlos J. Finlay: The mosquito man

    Enrique Chaves-Carballo Kansas City, Kansas, United States Portrait Dr. Carlos J. Finlay. From Images History of Medicine (IHM), National Library of Medicine. Carlos Juan Finlay was born in Puerto Príncipe (now Camagüey), Cuba, on December 3, 1833. He was sent to Europe to complete his secondary education but was forced to return to Cuba after…

  • African American contract doctors in the military

    Edward McSweeganKingston, Rhode Island, United States In the spring of 1898, the United States rushed into a war with Spain but lacked adequate troops, training, weapons, transport, supplies, food, landing craft, and medical personnel. One deficit that could be corrected before the shooting started was the lack of doctors. George Sternberg, the Army Surgeon General,…

  • The hunt for a yellow fever therapy

    Edward McSweegen Kingston, Rhode Island, United States   Roux’s syringe for delivering antitoxin, The College of Physicians of Philadelphia.  Source In March 2020, a research group in China reported the use of convalescent plasma to treat ten patients suffering from coronavirus COVID-19 infections.1 This type of therapy—passive immunization—dates back to 1891 when the German bacteriologist Emil…

  • How conflict and bureaucracy delayed the elimination of yellow fever

    Edward McSweeganKingston, Rhode Island, United States The Golden Age of Bacteriology (1876–1906) saw the emergence of techniques to cultivate bacterial pathogens and develop vaccines and anti-toxin therapies against them. The new bacteriologists rapidly identified the agents causing anthrax, gonorrhea, typhoid, tuberculosis, cholera, tetanus, diphtheria, plague, and other infectious diseases. One microbe that remained stubbornly elusive…