Tag: Simon Flexner
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The once fatal pernicious anemia
For much of medical history, pernicious anemia was a baffling and invariably fatal disorder. Characterized by profound weakness, pallor, glossitis, and progressive neurologic decline, it carried an ominous reputation. Its name—“pernicious”—reflected the despair of physicians who could offer no remedy. The symptoms of this disease… Read more
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On clubfoot, orthopedics, art, and history
Avi OhryTel Aviv, Israel A clubfoot,1 or congenital talipes equinovarus (CTEV), is a birth defect in which the foot is inverted. If untreated, children with TEV often walk on their ankles, or on the sides of their feet. The condition occurs about one in every… Read more
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Earl Bakken: Pacemaker pioneer and founder of Medtronic
Ahmed NadeemChicago, Illinois, United States Earl Bakken was an electrical engineer who developed the external, battery-operated, wearable pacemaker. He was born in Minnesota in 1924 and received his Bachelor of Science and Master of Science degrees in electrical engineering from the University of Minnesota. In… Read more
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Jacobus Rau: Surgical innovator, renowned lithotomist, and educator at Leiden
Johann Jakob Rau, latinized to Johannes, was one of the most influential surgical innovators of early modern Europe, best known for transforming the treatment of urinary bladder stones through his lateral lithotomy technique. Born in 1668 in Baden-Baden, he was the son of wine merchant… Read more
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Bernhard Siegfried Albinus: Anatomist and surgeon
Bernhard Siegfried Albinus, originally called Weiss, was born at Frankfurt on the Oder in 1697. There his father was professor of medicine until 1702 when he was transferred to the chair of medicine at Leiden University. Thus young Bernhard began his education in the Netherlands… Read more
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Agatha Christie’s first post-mortem
Stephen McWilliamsDublin, Ireland Aficionados of Hercule Poirot and Miss Marple could do worse than read Carla Valentine’s Murder Isn’t Easy: The Forensics of Agatha Christie.1 In the book’s introduction, we’re reminded that Christie, the “Queen of Crime,” remains the world’s all-time bestselling novelist, outsold only… Read more
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Lorenz Heister, German surgeon
Lorenz Heister (or Laurentius Heister in his Latin works) was a prominent German general, eye surgeon, and professor of anatomy and surgery at the University of Altdorf, Germany. Heister contributed significantly to surgical practice, particularly through his influential surgical books, which hold a place in… Read more
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A second mind in scientific writing
Rao UppuBaton Rouge, Louisiana, United States Clarity in scientific writing is a rare achievement. As Margaret Thatcher would have said in a different context, it does not fall from Heaven but needs work, often a lot of it. I learned this years ago, not in… Read more
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“These late eclipses … portend no good to us” – Shakespeare
Edward TaborBethesda, Maryland, United States Introduction Eclipses of the sun or moon were powerful images used by William Shakespeare in ten of his plays and poems.1 Shakespeare’s characters believed that eclipses were under the control of evil forces, that eclipses could predict the fall of… Read more
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The rise and fall of railway spine
Lenny GrantSyracuse, New York, United States By 1864, British railways were responsible for 36 deaths and 700 injuries annually.1,2 Yet the most perplexing cases were not the visibly wounded, but those passengers who walked away apparently unharmed, only to develop debilitating symptoms days or weeks… Read more
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A Polish tragedy and a case without a diagnosis
On the morning of September 1, 1939, German troops attacked Poland without a declaration of war. Two weeks later, on September 17, while Poland was defending itself in the west, the Soviet Union attacked from the east. This two-pronged attack was too much for Poland… Read more