Tag Archives: Richard Bright

A brief history of kidney transplantation

Laura Carreras-Planella Marcella Franquesa Ricardo Lauzurica Francesc E. Borràs Barcelona, Spain   We may think of renal transplantation as routine therapy today, but this procedure has taken centuries to develop and is marked by important events in the history of science. An ancient description of the kidneys is found in the Egyptian Ebers Papyrus, dated […]

Pierre Rayer (1793- 1867) – first to use microscopy to study kidney disease

Pierre Rayer occupies a special place in the history of nephrology for his attempt to classify the various diseases that Richard Bright had described in his monumental publication of 1827. With his intern Eugene Napoleon Vigla, he revolutionized the study of kidney diseases by using microscopy to analyze urinary sediments, describing crystals, cells, casts, and […]

History of nephrology: the middle period

George Dunea Chicago, Illinois, United States   Domenico Cotugno Coagulable urine Despite centuries of medical progress, the presence of abnormal amounts of albumin in the urine remains to this day the most sensitive and widely used indicator of renal disease. Described by Hippocrates as “bubbles on the surface of the urine” and known to medieval […]

Richard Bright, the father of nephrology

Two centuries will soon have passed since Richard Bright, of Guy’s Hospital, London, described the disease that came to bear his name. Within a few years of his original publication, the term Bright’s Disease became virtually synonymous with kidney disease—in England, Germany, France, and the United States. In its full-blown formulation it consisted of four […]