Hektoen International

A Journal of Medical Humanities

Tag: nephrology

  • Sir George Pickering and the low salt diet

    Nicolas Roberto RoblesBadajoz, Spain As a young man George Pickering was interested in his native Northumbrian countryside and intended to study agriculture. Persuaded later to read for a degree in biochemistry or physiology, he obtained a scholarship in basic sciences at Pembroke College, Cambridge, then decided to study medicine. He went to St. Thomas’s Hospital…

  • Sympathectomy for hypertension

    Sympathectomy for essential hypertension was introduced in the late 1920s at a time when no effective medical treatment was available. It consisted of resecting several sympathetic neurons that exit the spinal cord from the mid to lower spinal cord and are arranged in two columns of nodules called ganglia on either side of it. Sympathetic…

  • Walter Kempner (1903–1997) and his rice diet

    Walter Kempner, the doctor with the thick German accent who came to America to escape from the Nazis, was born in 1903. Son of two bacteriologists who had both worked on tuberculosis, he graduated in medicine from the  University of Heidelberg in 1928 and subsequently worked there and in Berlin. When the anti-Jewish laws were…

  • Harry Goldblatt and the kidney

    In 1928 Dr. Harry Goldblatt applied silver clamps experimentally to the renal arteries of dogs and observed a significant and sustained rise in blood pressure. His main interest as a researcher was to find a cause for hypertension, a disease for which effective treatment was not available at the time. There had been a long-standing…

  • A brief history of kidney transplantation

    Laura Carreras-PlanellaMarcella FranquesaRicardo LauzuricaFrancesc E. BorràsBarcelona, Spain We may think of renal transplantation as routine therapy today, but this procedure has taken centuries to develop and is marked by important events in the history of science. An ancient description of the kidneys is found in the Egyptian Ebers Papyrus, dated to 1550 BC and discovered…

  • Belding Scribner and his arteriovenous Teflon shunt

    Without Belding Scribner maintenance dialysis might have never happened. Although by 1960 the technology of hemodialysis had become quite advanced, and several types of dialyzers, notably the Kolff Twin Coil, had been successfully used, long-term access to the vascular system was still not available. The choice for the physician was to cut down on peripheral…

  • Satoru Nakamoto

    Of all the pioneers who made hemodialysis a reality, Satoru Nakamoto was the most humble and unassuming. He died in 2020 at the age of 92, almost forgotten by a generation that often takes the technical advances of dialysis for granted and rarely looks back on the people who made it possible. I had the…

  • Unlikely pioneers in renal transplantation: The Little Company of Mary Sisters

    Jayant RadhakrishnanDarien, Illinois, United States Dr. Joseph Murray deservedly received the Nobel Prize in 1990 for his magnificent pioneering work in the field of renal transplantation.1 However, it is not widely known that religious sisters from the congregation of the Little Company of Mary also deserve much credit for their support of renal transplantation in…

  • Thomas Addis and his times

    Thomas Addis, one of the most prominent students of the kidney during the first half of the twentieth century, was born in Edinburgh in 1881.1-3 Recruited by Stanford Medical School University in 1911, he spent almost his entire academic life there. After a brief interest in hemophilia and bilirubin metabolism, he switched to the study…

  • Stanley Shaldon as I knew him

    Stanley Shaldon belonged to that first generation of nephrologists who made dialysis available at a time when uremia was a sentence of death. He was one of the bright young registrars whom Professor Sheila Sherlock took with her from the Royal Postgraduate Medical School at Hammersmith to the Royal Free Hospital to work on liver…