Omentum: much more than “policeman of the abdomen”
Ashok Singh Chicago, Illinois, United States Histology of activated omentum 3 days after placing a 5 cc slurry of inert polydextran particles of approx. 100 micron diameter (1 million particles) in the abdominal cavity of rats. Note the dramatic change in the size and quality of the omentum. While the native omentum is fatty […]
Augusta Ada Byron, Countess of Lovelace (1815–1852)
JMS Pearce Hull, England Fig 1. Charles Babbage. Engraving from 1871. Via the Library of Congress Prints and Photographs Division. Source It is undeniable that computer science and technology play an important part in medical investigation and research, and universally in the transmission of information. Everyone remembers Charles Babbage, (1791-1871) (Fig 1) inventor of […]
Doubled edged shield
Adil Menon Cleveland, Ohio, United States Jeryl Lynn Hilleman with her sister, Kirsten, in 1966 as a doctor gave her the mumps vaccine developed by their father. Unknown Photographer, distributed by Merck Sharp & Dohme. ca 1966. Credit: Smithsonian National Museum of American History Working my way through a biography of pioneering vaccine developer […]
Cancer and eye diseases: two birds killed with one stone, anti-VEGF antibody
Ashok Singh Chicago, IL, United States Tissue Richly Endowed with Blood Vessels Loss of blood vessels after the same tissue was treated with Anti-VEGF antibody Various cells in the human body, such as lymphocytes, monocytes, and all tissue cells release small proteins that, unlike hormones, which act at distant sites, have powerful effects on […]
Absinthe: the green fairy
Nicolás Roberto Robles Badajoz, Spain Figure 1. Green Muse. Albert Maignan. 1895. Via Wikimedia Commons “After the first glass of absinthe you see things as you wish they were. After the second you see them as they are not. Finally, you see things as they really are, and that is the most horrible thing […]
Kathleen (Yardley) Lonsdale DSc., FR
JMS Pearce Hull, England Fig 1. Dame Kathleen Lonsdale (née Yardley) by Elliott & Fry. 1996. National Portrait gallery. CC BY-NC-ND 3.0 Kathleen Lonsdale (1903-1971) (Fig 1) like her contemporary Dorothy Hodgkin was one of the women pioneers in a man’s world of professional scientists.1 She developed original techniques in X-ray diffraction of crystals […]
Dorothy Crowfoot Hodgkin OM, FRS (1910-1994)
JMS Pearce Hull, England Fig 1: Dorothy Hodgkin. by Godfrey Argent. National Portrait Gallery, London. CC BY-NC-ND 3.0. Dorothy Hodgkin (Fig 1), though not by religion, had close Quaker affinities through her marriage and through her spirited pacifism. She possessed a unique mixture of scientific skills that allowed her to extend the use of […]
John Dalton
JMS Pearce Hull, England Fig 1. John Dalton. Line engraving by W. H. Worthington, 1823, after J. Allen, 1814. Credit: Wellcome Collection. Attribution 4.0 International (CC BY 4.0) John Dalton (1766–1844) (Fig 1) is one of the most revered scientists of the last 250 years. His origins were humble. He was the son of Deborah and […]
Terminal digit preference
Marshall A. Lichtman Rochester, New York, United States Figure 1. There are three types of sphygmomanometer; mercury, aneroid, and digital. This figure is of a manual aneroid sphygmomanometer. The rubber pump is used to raise the cuff pressure above the patient’s systolic pressure and then the pressure is released by unscrewing slowly the small […]
The Doctors Cori, carbohydrate metabolism, and the Nobel prize
Beta-d-glucose. Image by Rob Hooft, via Wikimedia. CC BY-SA 3.0 Energy in animals and humans is stored in the body in the form of glycogen. Starch, a similar molecule but less branched, serves the same function in plants. Glycogen, discovered by Claude Bernard in 1856, is stored primarily in the liver (about 120 grams) and […]