Hektoen International

A Journal of Medical Humanities

Tag: smallpox

  • “An ounce of prevention”: past and present

    Jack E. RiggsMorgantown, West Virginia, United States Donald R. NewcomerGlendale, Arizona, United States Being old and lame of my Hands, and thereby uncapable of assisting my Fellow Citizens, when their Houses are on Fire; I must beg them to take in good Part the following Hints . . . In the first Place, as an…

  • The wonderful world of vaccines

    Jayant RadhakrishnanChicago, Illinois, United States Epidemics and pandemics became an issue about 10,000 years ago when hunters and gatherers became farmers and began to live in communities. Smallpox was one of the first lethal infections that spread widely. Its stigmata are seen in Egyptian mummies dating to 1570-1085 BCE. By 1500 CE, in China, India,…

  • Book review: Casanova’s Guide to Medicine

    Arpan K. BanerjeeSolihull, United Kingdom The eighteenth-century Italian Giacomo Casanova (1725–1798) is today best remembered for legendary amorous pursuits that resulted in his name becoming a part of the English language. What has been forgotten, however, is that he was a remarkable and erudite polymath. He graduated as a lawyer from the University of Padua…

  • Oswaldo Cruz and the eradication of infectious diseases in Brazil

    Robert PerlmanChicago, Illinois, United States In 1899, an epidemic of bubonic plague caused a crisis in the Brazilian port city of Santos. Ship captains were angry that their boats had to remain in quarantine and so denied that the disease was plague. They and others argued that this new disease was not as deadly as…

  • George Crile Sr., founder of the Cleveland Clinic

    Early days George Crile was an exceptional man, a skilled surgeon who lived at a time when American medicine was emerging from its horse and buggy period and was embracing the principles of aseptic surgery and scientific medicine. Always full of new ideas, he was first to carry out a human-to-human blood transfusion. He made…

  • Mortality data, risk probability, and the psychology of assent in the enlightenment smallpox debate

    David SpadaforaPinehurst, North Carolina The present health crisis is hardly the first to provoke significant controversy about preventing and treating widespread disease. Debate over epidemic-related data, its reliability, and its uses has a long history. So does concern about the psychological elements involved in securing assent from physicians and an endangered population for the use…

  • Abraham Lincoln’s smallpox

    Howard FischerUppsala, Sweden A brutal, bloody civil war had been tearing the United States of America apart for two years when President Abraham Lincoln arrived in Gettysburg, Pennsylvania on November 19, 1863. Four months before his visit, Gettysburg had been the site of a major battle between the secessionist Confederacy of the southern, slave-holding states…

  • Book review: Viruses, Plagues, and History by M. B. A. Oldstone

    Arpan K. BanerjeeSolihull, United Kingdom The first edition of Viruses, Plagues, and History was published to great acclaim twenty years ago and has now been updated to include the pandemics of the twenty-first century. These include the SARS, MERS, and Zika virus outbreaks, which have now been eclipsed by COVID-19. The early story of the…

  • Girolamo Cardano: Renaissance physician and polymath

    Born at Pavia in the duchy of Lombardy in 1501, Girolamo Cardano practiced medicine for fifty years but is remembered chiefly as a polymath. He composed 200 works, made important contributions to mathematics and algebra, invented several mechanical devices (some still in use today), and published extensive philosophical tracts and commentaries on the ancient philosophers…

  • The global journey of variolation

    Mariel TishmaChicago, Illinois, United States Humanity has eliminated only one infectious disease—smallpox. Smallpox is a very old disease and efforts to prevent it are almost as old. They included a technique called variolation, also known as inoculation or engrafting, in which individuals were infected with live smallpox virus to produce a milder form of the…