William Harvey before King Charles I
In 1628 William Harvey published his classic work De Motu Cordis (Of the Motion of the Heart and Blood in Animals) demonstrating that the blood passed from the left ventricle to the capillaries at the periphery and back through the veins to the right side of the heart. He received many honors for his work, and […]
Early clinical and molecular discoveries in Long QT Syndrome
Göran Wettrell Sweden Fig. 1 Anton Jervell, Norwegian physician, hospital manager and later professor at the University of Oslo with research on heart diseases. Source Sudden and unexpected death in people who are less than thirty-five years of age is associated with negative autopsy results in forty percent of cases.1 Long QT Syndrome (LQTS) […]
Human heart in Descartes’s De Homine
The famous philosopher René Descartes had an interest in physiology. But although he is known to have carried out dissections and even vivisections, he was a theoretician and not an experimentalist. In 1643 he wrote that having read William Harvey’s 1628 De Moto Cordis he agreed with the theory that the blood circulated through the […]
Character, genius, and a missing person in medicine
Carrie Barron Austin, Texas, USA The Calling “He is the most un-talked about, unacknowledged, unknown and most important figure in the African American community… A genius.”1 In 1944, a surgeon with his trusted guide by his side performed the very first open-heart surgery on a fifteen-month-old, nine-pound girl. 1930 Nashville. A twenty-year old African […]
William Heberden on angina pectoris, 1772
“There is a disorder of the breast marked with strong and peculiar symptoms, considerable for the kind of danger belonging to it, and not extremely rare . . . The seat of it and the sense of strangling and anxiety with which it is attended, may make it not improperly be called angina pectoris. […]
Cecil Rhodes: The man with a hole in his heart
There must be few people in the world who can locate with confidence Northern or Southern Rhodesia on a map of Africa. Yet these countries still exist, only the names have changed. Nor would the man who founded them win a contemporary popularity contest. In fact, his statue at the University of Cape Town was […]
Dominic Corrigan (1802-1880)
In the days when students were expected to have at least a smattering of medical history, they would have known that Corrigan’s sign and pulse were indicative of aortic regurgitation and would have guessed that Corrigan was Irish. Very few, if any, would have known about Corrigan’s cirrhosis, Corrigan’s button, or the maladie de Corrigan.1 […]
Grokking: Cardiac rehabilitation by another name
Janice Kehler Chris Kehler Middleton, Wisconsin, United States Grokking: to understand with empathy “It is a life-saving intervention,” said Dr. Randall Thomas, the director of the Cardiac Rehabilitation Program at the Mayo Clinic in Rochester, adding that participation rates were abysmal. Only 20% of eligible patients over the age of sixty-five enroll in cardiac […]
Ibn al-Nafis and the pulmonary circulation
Medical advances are often made over long periods of time, making it difficult to assign priority to any particular individual. Such has been the case for the ”discovery” of the pulmonary circulation, a distinction variously assigned to three anatomists of the sixteenth century, Michael Servetus, Realdo Colombo, and Andrea Cesalpino. But in 1924 the Egyptian […]
Coronary moments: reflections on the impossible anastomosis
Jason J. Han Philadelphia, Pennsylvania, USA Coronary artery bypass surgery The arteries of the heart are called coronary arteries, meaning “of a crown.” Like a crown, they course around and adorn the walls of the heart, keeping it alive with vital nutrients and oxygen. When these arteries are blocked, the heart starves, causing crushing […]