Tag: Penicillin
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“Scarlet letters” — The depiction of scarlet fever in literature
Emily BoyleDublin, Ireland Scarlet fever, named for the erythematous skin rash that may accompany streptococcal infections (Fig 1), is often considered a disease of Victorian times. Associated with high levels of morbidity and mortality (up to 25%) when epidemics were common in the eighteenth and nineteenth centuries in Europe and the US,1,2 it is seen less…
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Sir Alexander Fleming: A microbiologist at work and play
Jayant RadhakrishnanDarien, Illinois, United States Sir Alexander Fleming had many talents. His discoveries of lysozyme in 1923 and in 1928 the antibiotic effect of the fungus Penicillium notatum are well known.1 Less well known is that he was a skilled marksman and a member of the London Scottish Regiment during World War I. There is…
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Gilgamesh and medicine’s quest to conquer death
Anika KhanKarachi, Pakistan “O Uta-napishti, what should I do and where should I go?A thief has taken hold of my [flesh!]For there in my bed-chamber Death does abide,and wherever [I] turn, there too will be Death.”—From The Epic of Gilgamesh, The Standard Version, Tablet XI1 “O Uta-napishti, what should I do and where should I…
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St. Mary’s Hospital, birthplace of penicillin
Anabelle S. SlingerlandLeiden, NetherlandsKevin BrownLondon, England On April 23, 2018, Prince William and the Duchess of Cambridge left the Lindo Wing of St. Mary’s Hospital in London with their new baby boy. Fans of the Royals, who had been camping outside St. Mary’s for weeks, and the crowds and photographers who had gathered for the…
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Women changing medicine
Lesley CampbellDarlinghurst, New South Wales, Australia This is my account of three generations of women doctors in my family who in different times and different places were subjected to persecution or at least discrimination because of their race, religion, and gender. The account is written in the hope that society in general and medicine in…
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Chance in the origins of antibiotics
William KingstonDublin, Ireland The discovery of antibiotics has been described as the “domestication of microorganisms” and ranks in importance with the domestication of animals as part of settled agriculture about 10,000 years ago. It depends upon antagonism between bacteria, which had been noticed as early as 1874, and Pasteur commented then that if we could…
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Lord Howard Florey and the use of visual art in medicine
Vincent CracoliciChicago, Illinois, United States Art and medicine: Skills for creative problem solving Despite similar training, all physicians are not equally skilled in recognizing and solving clinical problems. Those who have been remarkably innovative in their specialty often share similar characteristics with one another. Though gifted in the technical aspects of their fields, many of…