Tag: neurosyphilis
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Douglas Argyll Robertson and his pupils
JMS Pearce Hull, England Figure 1. Argyll Robertson pupil reactions. Diagram by Chainwit. on Wikimedia. CC BY-SA 4.0. In my student days, the Wasserman reaction (WR), though not specific, was performed almost routinely in patients on medical wards to detect syphilis. Several direct and serological tests of varying sensitivity and specificity have now replaced…
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Diagnosing Mona Lisa
Howard FischerUppsala, Sweden “Mona Lisa looks as if she has just been sick, or is about to be.”– Noel Coward Leonardo da Vinci (1452–1519) was a many-talented genius of the Italian Renaissance. He was a painter, anatomist, engineer, and inventor. One of his best known paintings, a portrait of a noblewoman, is called the Mona…
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Diagnosis: Neurosyphilis. Treatment: Malaria, iatrogenic
Howard Fischer Uppsala, Sweden Patient in Kettering hypertherm cabinet undergoing fever therapy. New Orleans, 1937. U.S. Marine Hospital. Works Progress Administration photo. New Orleans Public Library Digital Collections via Wikimedia. Public domain. “The syphilitic man was thinking hard…about how to get his legs to step off the curb and carry him across Washington Street.…
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Frederick Delius and his neurological disease
Photograph of Frederick Delius. 1907. From Monographien moderner musiker. Via Wikimedia. The life of the English composer Frederick Delius and his tragic encounter with the spirochaeta pallida has been extensively documented. He was born in 1862 in the industrial Yorkshire town of Bradford. His family had come to England from Germany but was originally Dutch,…
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Can behavioral variant frontotemporal dementia salvage Semmelweis?
Faraze A. Niazi Jack E. Riggs Morgantown, West Virginia, United States Ignaz Semmelweis. 1818 – 1865. Age 47 years at death. Via Wikimedia. Remember me for the mind I had; not the mind a disease created. Few physicians have made a more significant observation than did Ignaz Semmelweis.1 In 1847 he took over two…
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Heinrich Heine and the mattress tomb
Nicolás Roberto Robles Badajoz, Spain Harry Heine was born in Bolkerstrasse, Düsseldorf, Germany. He jokingly described himself as the “first man of the century,” claiming that he had been born on New Year’s Eve 1800. Researchers have discovered, however, that December 13, 1797, is most likely the date of his birth. The oldest of…
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Friedrich Nietzsche—much afflicted philosopher
Friedrich Nietzsche by Edvard Munch. 1906. Thielska Gallerie, Sweden. Via Wikimedia. Friedrich Nietzsche was one of the most important philosophers of the nineteenth century. Though often misinterpreted, his influence has been enormous. Like his compatriot Schopenhauer, he questioned the comfortable beliefs of the conservative bourgeoisie of his time. His writings have fascinated generations of readers,…