Hektoen International

A Journal of Medical Humanities

Tag: engrafting

  • The global journey of variolation

    Mariel TishmaChicago, Illinois, United States Humanity has eliminated only one infectious disease—smallpox. Smallpox is a very old disease and efforts to prevent it are almost as old. They included a technique called variolation, also known as inoculation or engrafting, in which individuals were infected with live smallpox virus to produce a milder form of the…

  • Lady Mary Wortley Montague: variolation against smallpox

    Born in 1689, Lady Mary Wortley Montague was the most colorful Englishwoman of her time—an eccentric aristocrat, writer, and poet. In 1715 while still a young woman, her beauty was marred by a severe attack of smallpox. She had eloped in 1710 rather than accept an arranged marriage, and in 1715 her husband became British…