Hektoen International

A Journal of Medical Humanities

Tag: DNA

  • Gregor Johann Mendel, father of modern genetics (1822–1884)

    Gregor Mendel was an Austrian scientist and Augustinian friar who laid the foundation of the science of heredity and genetics. Although his contributions to science were not widely recognized during his life, his work with pea plants in the mid-19th century revolutionized our understanding of how traits are inherited across generations, thus greatly influencing medicine,…

  • Will DNA be the next invisible ink?

    Edward TaborBethesda, Maryland, United States Deoxyribonucleic acid (DNA), the chemical that forms our genes, can be used to encode and transmit narrative documents and photos, as shown in several published studies. DNA might also become the next “invisible ink” because messages in DNA can be “hidden in plain sight” to reduce the chance of being…

  • Gain of function

    Jayant RadhakrishnanDarien, Illinois, United States “It is no good to try to stop knowledge from going forward. Ignorance is never better than knowledge.”– Enrico Fermi (1901–1954) “Gain of Function” (GoF) burst into the general lexicon in 2021 during two shouting matches in the US Senate between the Junior Senator from Kentucky and the Director of…

  • The mystique of psychiatry: a closer look

    Lawrence ClimoLincoln, Massachusetts, United States As a retired psychiatrist, I have been thinking about the mystique that surrounds our profession. Psychiatrists seem to trigger three provocative associations that set them apart from other physicians. The first, sometimes interpreted as a wish, is that psychiatrists read minds and therefore know what is concealed or hidden inside…

  • A note on handedness

    JMS PearceHull, England, United Kingdom Handedness (chirality) refers to the preferential use of one hand over the other. It is a matter of degree; it is seldom absolute. Population left and right preference existed in the Neanderthals (lived from 400,000 to about 40,000 years ago) onwards. Only homo sapiens amongst the great apes shows strong…

  • Trijntje Keever—a tall tale

    Orit Pinhas-HamielHamiel UriTirosh AmitRamat Gan, Israel There is a life-size painting in the city of Edam in The Netherlands that portrays a girl who is exceptionally tall with disproportionately long hands. The artist is unknown, but the name of the girl in the picture is Trijntje Keever. Trijntje was born in April 1616, the daughter…

  • Review: The History of the World in 100 Pandemics, Plagues and Epidemics

    Arpan BanerjeeSolihull, United Kingdom The publication of this book could not have been better timed. The book sets out to show how pandemics, epidemics, and infectious diseases have shaped human history over the last 5,000 years. Its contents help us place the current COVID-19 epidemic in its rightful historical context. Famine, war, and pestilence have…

  • A look back at insulin

    Shrestha SarafSutton Coldfield, United KingdomSanjay SarafSudarshan RamachandranBirmingham, United Kingdom As we approach the centenary of the isolation, purification, and clinical use of insulin, it is an appropriate moment to reflect on the impact of this hormone on the management of diabetes. Diabetes can be defined as a heterogeneous group of conditions resulting in high blood…

  • Painting an ICU

    Mark TanNorthwest Deanery, England, United Kingdom “[Monet was] only an eye – yet what an eye.”— Paul Cézanne Much has been written about Claude Monet’s ophthalmic pathology.1-4 However, attributing his stylistic development to cataracts alone seems an overly reductionist view. In 1874, at least fifteen years before his Japanese Bridge and Water Lilies series, his…

  • Mitochondrial DNA: a maternal gift

    Marshall LichtmanRochester, New York, United States DNA is arrayed on twenty-three pairs of chromosomes in human cell nuclei. It is coiled tightly around proteins called histones that together with DNA form a chromosome. The largest chromosome carries several thousand genes and the smallest several hundred. DNA is so tightly wound that uncoiled from a single…