Tag: Cardiology
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Alain G. Cribier, MD, aortic stenosis, and TAVI
Daniel GelfmanIndianapolis, IN In 2024, the world of interventional cardiology lost one of its greatest innovators: Alain Cribier, MD (1945–2024). Called the father of “structural heart disease” treatment and described as “larger than life, he was a Renaissance man, fluent in English and French, knowledgeable in philosophy and art, but keen to be a physician…
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From bedside to bench: The discovery of calmodulinopathy
Göran WettrellLund, Sweden As a pediatrician specializing in pediatric cardiology, I met in 1982 a twelve-year-old-boy with syncope when playing football. He had four previous episode of losing consciousness during physical activity and once during a fire alarm. His resting ECG was normal but his long-term ECG registration revealed exercised-induced ventricular extrasystoles of increasing complexity.…
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Sunao Tawara
Sunao Tawara was a prominent Japanese pathologist and anatomist best known for discovering in 1906 the atrioventricular node, also known as the AV node or bundle of Tawara. This small mass of specialized cardiac muscle fibers located between the atria and ventricles of the heart is a key component of the heart’s conduction system, responsible…
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Rene Favaloro—Father of cardiac bypass surgery
Arpan K. BanerjeeSolihull, England Over the last century, there have been many important contributions to medicine made by Argentinians. Of these Rene Geronimo Favaloro’s must surely be of the greatest, and his work on cardiac bypass surgery has saved countless of lives. Born of Sicilian ancestry on July 12, 1923, in La Plata, Argentina, Favaloro…
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Dr. Bernard Lown
Philip LiebsonChicago, Illinois, United States Sudden death from cardiac dysrhythmias is a frequent consequence of acute myocardial infarction. Before the 1960s, little could be done to prevent it, and patients were usually confined to bed for several weeks. Ventricular fibrillation, the underlying cause of sudden cardiac death, was a frequent occurrence. In the 1950s, Dr.…
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C. Walton Lillehei, father of open-heart surgery
Dr. Clarence Walton Lillehei (1918–1999) was born in Minneapolis, received his medical degree from the University of Minnesota in 1942, and spent his entire career on the staff of the University of Minnesota Medical School. In the early 1950s he began to experiment with cross-circulation, a technique in which the blood vessels of a patient…
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James Hardy, heart and lung transplant pioneer
James D. Hardy was an American surgeon who performed the world’s first human lung transplant in 1963 and human heart transplant in 1964. Born in Alabama in 1918, Hardy obtained his medical degree from the University of Alabama in 1942. He served in the army during World War II, then returned to the University of…
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Two giants in thoracic surgery: Clarence Crafoord and Åke Senning
Göran WettrellLund University, Sweden Clarence Crafoord Clarence Crafoord (1899–1984) was one of the most outstanding surgeons in Sweden during the twentieth century (Figure 1). He started his surgical training in the early 1920s. Postoperative complications such as obstructing pulmonary thrombosis were a frequent cause of death. In 1927, Crafoord performed two successful acute pulmonary embolectomies.1…
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Jean-Baptiste de Sénac and his early textbook on cardiology
Göran WettrellLund, Sweden William Harvey was an important figure in the early days of cardiovascular physiology. Based on meticulous observations, he published De Motu Cordis and Sanguinus in 1628 and has been proposed as the founder of physiology and cardiology.1 During the late seventeenth and early eighteenth centuries, physicians such as Raymond Vieussens (1641-1715), Giovanni-Maria…