Neurology – Hektoen International

Parkinson’s disease, the enduring eponym

The man who described what Jean Charcot six decades later called “la maladie de Parkinson” was a man of many parts. In his youth he studied Greek and Latin, and also learned shorthand, which he considered an essential skill for a doctor. He was an avid collector of fossils, minerals, and shells, and went on […]

Kinnier Wilson

Samuel Kinnier Wilson (1878-1937), one of the greatest neurologists of the first half of the twentieth century, described in 1912 under the title “progressive lenticular degeneration” what became known as “Wilson’s disease.” Born in New Jersey to a Scottish mother and an Irish missionary Presbyterian minister, he went to Scotland for his education, graduated from […]

William Alexander Hammond

JMS Pearce  Hull, England, United Kingdom   Figure 1. William Alexander Hammond In much of the nineteenth century, ”internal medicine” dominated medical practice in the United States. Specialism was widely disdained and faced hostility and scepticism,i, not least from the influential Sir William Osler: There are, in truth, no specialties in medicine, since to know […]

Pierre Marie (1853-1940)

Pierre Marie (1853-1940) was a French neurologist and native of Paris who after finishing medical school started as an intern under the famous neurologist Jean-Martin Charcot, worked through the ranks, and eventually was appointd to the chair of neurology at the Faculty of Medicine from 1917-1925. One of Marie’s early contributions was a description of acromegaly […]

Jules Dejerine

Jules Dejerine originated in Savoy and grew up in the then provincial atmosphere of Geneva, where his father was a carriage proprietor… Young Dejerine had a powerful physique. At the Lycée Calvin he was better known for his swimming and boxing then for his devotion to study…. Nevertheless, he did well in school…left for Paris […]

Multiple [disseminated] sclerosis

  “Disseminated sclerosis was described pathologically in the 1830s by Cruveilhier in Paris and Carswell in London, but clinical accounts were sketchy. It was known only to the cognoscenti and regarded as a great rarity. Charcot was the first to diagnose the disease during life, and from 1860 onwards Charcot and Vulpian, and later Charcot […]

Death from uremia

“Your grandmother is doomed,” [the doctor] said to me. “It is a stroke brought on by uremia. In itself, uremia is not necessarily fatal, but this case seems to me hopeless. I need not tell you that I hope I am mistaken.” [Then] there was a moment when the uremic trouble affected her eyes. For […]

Lewis Carroll’s Alice in Wonderland

Rayda Aaishah Joomun Mauritius   Diagram A: Total Macrosomatognosia Author Dedication To Deelshad Reezuana, The most beautiful Alice I met, May you rest in peace in Wonderland…   “Thus grew the tale of Wonderland: / Thus slowly, one by one, / Its quaint events hammered out / And now the tale is done, / And home we steer, a […]

Somnambulance and other surprises

Brent da Silva Russell Marietta, Georgia, USA   Palpation for tusks In one of the odder experiences of my life, I woke up in the middle of the night to find my wife prodding my face with her fingers. “What are you doing?” I asked. “I’m trying to see whether you have tusks,” she replied. […]

The human brain: writer of our stories

Jaleed Ahmed Gilani Karachi, Pakistan   The Human Brain, Home of our existence and the Writer of our stories. “What if I told you that this world around us, this richly textured world, were all just an illusion constructed in your head?” asks eminent neuroscientist David Eagleman in the brilliant documentary The Brain with David […]