Tag: Vignette
-
The diverticulum of Meckel
Johann Friedrich Meckel the Younger, a German anatomist, identified and described Meckel’s diverticulum in 1809, building on earlier observations by Fabricius Hildanus in the sixteenth century. The diverticulum is the most common congenital abnormality of the gastrointestinal tract, found in about 2% of the population. It is a pouch or bulge in the small intestine…
-
Francis Glisson and his capsule
Francis Glisson (1597–1677) was a highly successful physician, so famous in London that in 1668 he was consulted along with Ashley Cooper and Thomas Sydenham to advise whether the future Earl of Shaftesbury should undergo surgery to drain a perihepatic abscess. In 1650, he published a comprehensive account of infantile rickets (“Glisson’s disease”). Four years…
-
A gastrointestinal quartet
These four individuals, despite their promising, euphonious names, did not write great operas. They were mere anatomists and worked on the area where the pancreas and gallbladder ducts meet to enter the duodenum. The most senior of the group was the German Johann Georg Wirsung (1589–1643). While working in Padua in 1642 and dissecting an…
-
Sir Peter Medawar and the discovery of acquired immune tolerance
At Oxford during World War II, Peter Medawar and his colleagues made the remarkable observation that patients pre-treated in early life with embryotic cells did not reject skin grafts from unrelated donors. This gave rise to the concept of acquired immunological tolerance and revolutionized the field of organ transplantation as well as changed our understanding…
-
Love potions and aphrodisiacs
The ancient gods lived high atop Mount Olympus. They loved, quarreled, and meddled in human affairs. They had amongst them a goddess of love whom the Romans called Venus and the Greeks Aphrodite. In time, these names followed different trajectories. Venereal became what you get after a night with Bacchus and Venus. Mons Veneris, or…
-
Medical lessons from giraffes
There is a story of a man going to a zoo for the first time and, after staring at a giraffe in astonishment, exclaimed, ‘‘There ain’t no such animal!’’1 Yet African giraffes have long been known to Europeans. They are the tallest living land animals in the world, and more recently have interested medical researchers.…
-
Israel Spach the biographer and the Lithopedion of Sens
Avi OhryTel Aviv, Israel Israel Spach (Israele Spachio, Spachius) (1569–1610), was raised and studied in Strasbourg and later in Paris under Jean Riolan the Elder.1 He finished his medical studies at the University of Tübingen under Andreas Planer in 1581.2 In 1589 he returned to Strasbourg, where he married3 and lived until his death. The…
-
The organic food movement
The word organic in the context of chemistry refers to a substance built around a skeleton of carbon (unlike an inorganic substance that most often has no carbon in its formula.) In the world of food, however, organic means that the produce was grown under “natural” conditions, without antibiotics, growth hormones, pesticides, fertilizers, sewage sludge,…
-
The Painted Veil: Death from cholera in China
The 1925 novel The Painted Veil by Somerset Maugham derives its title from Percy Shelley’s 1824 sonnet, which begins “Lift not the painted veil which those who live / Call Life.” The action takes place during a cholera epidemic in which a missionary doctor quotes on his deathbed the final line of Oliver Goldsmith’s famous…
-
The Mauriacs
Avi OhryTel Aviv, Israel Dedicated to the memory of Dr. Howard Fischer (1947–2024). Three persons bearing the name Mauriac are remembered to have achieved a place of distinction in French literature and medicine. The most famous of these was François Charles Mauriac1 (1885–1970), “a French novelist, dramatist, critic, poet, and journalist,” author of A Kiss…