Tag Archives: variolation

Lady Mary Wortley Montagu and smallpox

JMS Pearce Hull, England   Fig 1. A painting of Mary Wortley Montagu by Jonathan Richardson the Younger. Via Wikimedia. There are few examples of people with no medical training who independently make significant advances in medical practice. One such person was the elegant, aristocratic Lady Mary Wortley Montagu (1689-1762)—daughter of Evelyn Pierrepont, 1st Duke […]

Lady Mary Wortley Montague: variolation against smallpox

Born in 1689, Lady Mary Wortley Montague was the most colorful Englishwoman of her time—an eccentric aristocrat, writer, and poet. In 1715 while still a young woman, her beauty was marred by a severe attack of smallpox. She had eloped in 1710 rather than accept an arranged marriage, and in 1715 her husband became British […]

Edward Jenner and the dairymaid

Smallpox has plagued mankind since time immemorial, causing huge epidemics with great loss of life and often changing the course of history. The disease could be prevented or ameliorated by variolation, the subcutaneous inoculation with fluid from smallpox lesions into non-immune individuals. Variolation had been used for centuries, even for members of royal families. It […]