James R. Wright Jr.Calgary, Alberta, Canada In 1921, Fred Banting and Charley Best, working under the supervision of JJR Macleod, made crude pancreatic extracts from duct-ligated dog, fetal bovine, or whole adult bovine pancreata and used these to treat diabetes in depancreatized dogs. On January 23, 1922, Walter Campbell administered a pancreatic extract purified by…