Tag: State Lunatic Asylum of South Carolina
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Corn, pellagra, and modern medicine—How an ancient disease was recognized in South Carolina’s state lunatic asylum
Brody FoglemanHarsh JhaNoel BrownleeJuliSu DiMucci-WardSpartanburg, South Carolina, United States Pellagra is a disease of vitamin B3 (niacin) deficiency. Niacin is the precursor for many physiologic processes involving nicotinamide adenine dinucleotide (NAD), an enzyme that carries out long biochemical processes essential to a wide range of metabolic functions. While the understanding of niacin physiology is relatively…