Hektoen International

A Journal of Medical Humanities

Tag: Infectious Diseases

  • Koch’s postulates revisited

    JMS PearceHull, England Van Leeuwenhoek (1632–1722), a Dutch botanist, using his early microscope observed single-celled bacteria, which he reported to the Royal Society as animalcules. The science of bacteriology owes its origin to two scientists of coruscating originality, Louis Pasteur and Robert Koch. Pasteur may be described as master-architect and Koch as master-builder of the…

  • Leprosy and armadillos: Handle with care

    Howard FischerUppsala, Sweden Leprosy (Hansen’s disease) is a chronic, disfiguring, and handicapping infectious disease. It was known in the ancient world, and evidence of the disease has been found from 2000 B.C.1 In the sixth and seventh centuries it spread in Europe, peaking in incidence in the thirteenth and fourteenth centuries.2 The disease may have…

  • Rapid testing for the masses

    Anthony PapagiannisThessaloniki, Greece Ten young girls are queueing outside the makeshift surgery. They are between eleven and fifteen, they wear face masks, they giggle and tease each other and try to encourage the timid ones before the coming ordeal. What is this going to be? Their first visit to a gynecologist? Nothing so memorable. They…

  • Gain of function

    Jayant RadhakrishnanDarien, Illinois, United States “It is no good to try to stop knowledge from going forward. Ignorance is never better than knowledge.”– Enrico Fermi (1901–1954) “Gain of Function” (GoF) burst into the general lexicon in 2021 during two shouting matches in the US Senate between the Junior Senator from Kentucky and the Director of…

  • Dr. Oriol Mitjà: seeking to understand old and new infectious diseases

    Howard FischerUppsala, Sweden “Research needs to give answers to real problems.”– Dr. Oriol Mitjà Dr. Oriol Mitjà (b. 1980) earned his M.D. degree from the University of Barcelona. He then completed an internal medicine residency, followed by a fellowship in infectious disease. He earned a Diploma in Tropical Medicine and Hygiene from the London School…

  • Dr. Gerhard Domagk and prontosil: Dyeing beats dying

    Howard FischerUppsala, Sweden “It’s not that I’m so smart, it’s just that I stay with problems longer.”– Albert Einstein Dr. Gerhard Domagk (1895–1964) was a German pathologist and bacteriologist whose research led to a discovery that saved innumerable lives. He worked for the Bayer chemical company and was also a professor at the University of…

  • Robert Koch, M.D., and the cure for sleeping sickness: ethics versus economics

    Howard Fischer Uppsala, Sweden Primum non nocere. (First, do no harm.)— Hippocrates Robert Koch, M.D., (1843–1910) started his career as a country doctor and discovered the causes of tuberculosis, anthrax, and cholera. He is considered to be, along with Louis Pasteur, the founder of the field of bacteriology. Awarded the Nobel Prize for Medicine and Physiology…

  • Scotland’s Anthrax Island

    Howard FischerUppsala, Sweden “They make a desolation and call it peace.”— Agha Shahid Ali (1949–2001) During World War Two, the British government purchased from its owners the Gruinard Island, a one by two km island off the Scottish coast. The one inhabitant was evicted, and the island became the site of secret tests to weaponize…

  • AIDS: Thru a glass darkly

    S.E.S. MedinaBenbrook, Texas, United States I sat in the deep, cool shade of a stout, leafy Texas cedar escaping the torrid summer heat, idle thoughts meandering. Cotton-ball clouds grazed lazily across their azure prairie. The pervasive insane miasma swirling like a whirlwind around COVID-19 reminded me of days past when a very different virus dominated…

  • “Killed By Vaccination”: the enduring currency of a nineteenth century illogic

    Saty Satya-MurtiSanta Maria, California, United States Vaccine misinformation and anti-vaccination conspiracy theories are not new but have acquired a combative energy during the Covid-19 pandemic. Nearly all the arguments now raised against vaccination were known in the late nineteenth-century, and the vaccine objectors’ rhetoric shows striking similarities to that in use today. Smallpox vaccine opponents:…