Tag: hemoglobin
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From silks to science: The history of hematoxylin and eosin staining
Vidhi Naik Aberdeen, Scotland A slice of logwood, notably depicting its deeply colored heartwood, atop different fabrics stained by logwood dye. Image obtained and published with permission from Botanical Colors. Introduction Hematoxylin and eosin, dyes used to stain tissue samples, collectively known as H&E, form the benchmark for histological stains. These dyes possess a…
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Dr. Marilyn Gaston’s lifesaving research
Howard FischerUppsala, Sweden “[W]e can seize the opportunity to honor the too-often-neglected accomplishments of [B]lack Americans in every endeavor throughout our history.”1– President Gerald Ford, 1976 Marilyn Gaston, MD (b. 1939), grew up in a poor family, with both parents working at low-wage jobs. She graduated from the University of Cincinnati College of Medicine in…
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Book review: A Place in History: The Biography of John C. Kendrew
Arpan K. BanerjeeSolihull, United Kingdom Remarkable scientific advances in the twentieth century were also crucial for the field of medicine. In the new field of molecular biology, for example, scientists applied the principles of physics and chemistry to elucidate the structure of important proteins and molecules in the human body. John Kendrew was one of…
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Book review: Architects of Structural Biology
Arpan K. BanerjeeSolihull, United Kingdom Modern twenty-first-century high-technology medicine, which we now take for granted, was only made possible by remarkable advances in the physical and biological sciences of the twentieth century. In Architects of Structural Biology, the contributions of four scientific giants and Nobel laureates—Lawrence Bragg, Max Perutz, John Kendrew, and Dorothy Hodgkin—are described…
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Training wheels
Shannon KernaghanAlberta, Canada From the beginning of Paul’s dance with doctors, I have sat next to him and squeezed his hand through the pronouncement of hemochromatosis. The first doctor said his high iron level, if left untreated, would make him sicker than he already felt, possibly kill him. The laundry list of complications started with…
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Avant garde research on a blood substitute at the Hektoen Institute of Medical Research
Jayant Radhakrishnan Darien, Illinois, United States From Left to Right: Gerald S Moss MD, Richard Brinkman MD, Lakshman Sehgal PhD, Robert Forest DVM. June 1975, photograph of the team with the first baboon resuscitated with stroma free hemoglobin after being bled down to a hemoglobin concentration of zero. Photo taken by the author. The…
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A real world of not-so-real blood
Kelsey RuudSpokane, Washington, United States Sarah Smith* thought today would be like any other day. She would take her kids to school, then go to her job as an office secretary. But Sarah never made it. Passing through an intersection, Sarah’s car was hit when another driver ran a red light. Paramedics arrived at the…
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Spherocytosis
Andrea LolloNew York, New York, United States “Hereditary spherocytosis is a common inherited disorder that is characterised by anaemia, jaundice, and splenomegaly.”1 It was odd, of course, for a ten-year-old to have gallstones. It was even stranger for me to miss a full week of summer camp to sleep on the couch, swimming in and…
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Taking the bat out of Hell
Tajri Salek Birmingham, UK Fig. 1 The Destruction of Job’s Sons, from Illustrations of the Book of Job, 1825–26. Engraving by William Blake. Collection in the Metropolitan Museum of Art. Copyright: Public Domain, Universal (CC0 1.0). “Listen to them, the children of the night. What music they make!” ― Bram Stoker, Dracula If you…
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First blood
John Graham-PoleAntigonish, Nova Scotia, Canada Hospital for Sick Children, Great Ormond Street, London, 1970: I’m astounded I’ve landed one of the coveted G.O.S. senior resident jobs. The academic nature of the place immediately daunts me. Everyone bows down to its status as the foremost pediatric research hospital in Europe, perhaps in the world, the faculty…