Tag: chemotherapy
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Childhood cancer: Where my shadow fell
John Graham-PoleAntigonish, Nova Scotia, Canada In this essay, I reflect on my journey as a pediatric oncologist—from a time when childhood cancer was nearly always fatal to the gradual emergence of cures. Drawing on personal experiences with patients and their families, I examine the medical milestones, ethical complexities, and emotional burdens that shaped my career…
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The history of chemotherapy
Jayant RadhakrishnanChicago, Illinois, United States When Sahachirō Hata developed a cure for syphilis while working in Paul Ehrlich’s laboratory,1 Ehrlich began to look for other chemicals that could destroy infectious agents without affecting normal host cells. In 1907, he coined the term chemotherapy2 and declared that “the optimal agent would combine high parasitotropism with low…
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Void’s flame
Xuchu LiBeijing, China In late autumn’s golden embrace,scarlet maple leaves softly caress you,a mild exhaustion sensed,a months-long struggle persists.The tumors burgeon and spread like violet flamesupon your withered, skeletal frame—a desolate scene, frail and lame.Each breath feeds its growth.Scalding sweat on your brow,defiant tears in your eyes, unable to dispel it.Yet you fight, through dawn…
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Saying goodbye
Anthony PapagiannisThessaloniki, Greece Her head is bald, her face pale. Only a couple of weeks have passed since her latest cycle of chemotherapy, which imposed its ravages but offered no benefit. The disease is marching relentlessly ahead, the survival horizon drawing closer each day. She is alive only with the help of strong medications that…
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Disaster code
Nohad MasriBeirut, Lebanon It was six in the evening and we were finishing our hematology board virtual meeting. Because COVID-19 cases were again on the rise, the hospital staff was working at half capacity, with the other half at home. The chemotherapy unit patients had finished their treatments and the nurses were writing up their…
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Modern day obstinacy: the persistence of pangalintaw
Halima AbdulmaguidNorth Cotabato, Philippines In the first week of June, my mother was rushed to the hospital because her cough was getting worse and her shoulder pain no longer bearable. On her x-ray film we saw that half of her lungs were not visible; there was fluid inside causing the obscurity, and there was also…
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Parental grief
Ellen ZhangBoston, Massachusetts, United States We didn’t know the ending because this was usback then. Sometimes wanting is not enough.When the oncologist spoke. While you startedto cry only because your mother did. As we cradledyou gently. Beyond the singularity of such moments. There is a universal grieving for parents losing a child.All things lead to…
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Twins
John Graham-PoleClydesdale, Nova Scotia, Canada Why was she taken? While you remain to question me for your school project? Renee had a project. Her seventh-grade class had been set the task of composing an essay on some aspect of American society. She had settled on tackling the American healthcare system, and after some thought had…
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The first effective chemotherapy for cancer
Marshall A. LichtmanRochester, New York, United States Sulfur mustard gas had no influence on the outcome of the battle at Ypres during World War I despite the many deaths and severe injuries it inflicted. Since then, chemical weapons have been used in conflicts at least fifteen times between 1919 and 2016—in the Iraq-Iran War, by…