Tag: anemia
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Thalassemia
David GreenGeorge HonigGeorge DuneaChicago, Illinois, United States The thalassemias comprise a large and diverse group of genetic disorders which share as a common feature a deficiency, or in the most severe forms a total absence, of one or more of the globin chains of hemoglobin. It was first recognized as a clinical entity distinct from…
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Diagnosis: Neurosyphilis. Treatment: Malaria, iatrogenic
Howard FischerUppsala, Sweden “The syphilitic man was thinking hard…about how to get his legs to step off the curb and carry him across Washington Street. Here was his problem: His brains, where the instructions to his legs originated, were being eaten alive by corkscrews.”– Kurt Vonnegut, The Breakfast of Champions Julius Wagner-Jauregg, M.D. (1857–1940) graduated…
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Andersonville, Georgia and Elmira, New York: When Hell was on Earth
Howard FischerUppsala, Sweden “Abandon all hope, ye who enter here”— Dante Alighieri, Divine Comedy When the American Civil War (1861–1865) began neither the Union nor the Confederacy gave much thought to housing prisoners-of-war (POWs). Eventually, the two opposing sides had a total of about 120 POW camps.1 The two armies had captured a total of…
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My health care crisis
Yessenia GutiérrezMiami, Florida, United States “Mom, will it hurt?” These were the first words that came out of my mouth the day after my kidneys stopped working. The day after I found out that I had kidney failure and had to get a fistula in my arm for dialysis. I was very afraid because I…
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The novice
Charles HalstedDavis, California, United States Living in the convent at age eighteen, the novice practiced vows of poverty, chastity, and obedience. All she ate was in vain, the more she prayed, the more weight she lost, the weaker she became. I discovered her thin and frail in my clinic. Her stature was a striking feature,…
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Heterozygous advantage: How one deadly disease prevents another
Neal KrishnaBoston, Massachusetts, United States Of all the genetic disorders to which man is known to be a victim, there is no other that presents an assemblage of problems and challenges quite comparable to sickle cell anemia. Because of its ubiquity, chronicity, and resistance to treatment, sickle cell anemia remains a malady whose mitigation and…
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The paradox of blood donation
Beukou SteveLimbe, South-West Cameroon “Please I urgently need a donor who is blood group O rhesus negative for my sister to be operated. Please tell any of your friends.” These types of messages have become the newest type of notifications on our social media platforms in Cameroon. The notifications, while made up of different combinations…
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The smartest vampire story
Alice TheibaultRochester, New York, United States There is something uniquely terrifying about vampires. The concept of a nocturnal creature showing up at one’s home to suck their blood is enough to make just about anyone uneasy, and so vampires have been mined as a horror device for generations. Bram Stoker’s Dracula, which is arguably the…
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Diamond-Blackfan anemia and tap shoes
Jill PurteeSurprise, Arizona, United States Forty years ago I worked in a four-bed pediatric intensive care unit nestled in the pediatric ward. Every few weeks amongst the beeps and alarms, I heard the clicking of tap shoes coming down the pediatric ward hallway. My morning hug from Alma, a young girl with Diamond-Blackfan anemia, followed…