Tag: anatomy
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Marie François Xavier Bichat (1771–1802)
In the universal Pantheon of the medical greats, Xavier Bichat is remembered as “the father of modern histology.” Yet he never used a microscope. He studied the human organs with his naked eye and evaluated them for their physical features (such as elasticity, transparency, and hardness). He postulated that each organ was not a homogenous…
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Forensic medicine and Sir Bernard Spilsbury
JMS PearceHull, England A forensic autopsy performed to establish the cause of death is an ancient practice.1 In Europe it was preceded by conventional pathology, as started by Herophilus of Chalcedon (335–280 BC). Medicolegal autopsies to solve legal problems were first performed in Bologna in 1302. During the Middle Ages, physicians’ opinions were sought to…
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Seasick: Lessons in human anatomy from Hyman Bloom’s The Hull (1952)
Liz IrvinWorcester, Massachusetts, United States “I experience a gagging sensation and, still farther down, spasms in the stomach, the belly; and all the organs shrivel up the body, provoke tears and bile, increase heartbeat, cause forehead and hands to perspire.”– Julia Kristeva, Powers of Horror A cold dread crept up the back of my neck…
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Anna Morandi, famous anatomist of Bologna
Anna Morandi Manzolini (1714–1774) was an Italian anatomist and sculptor who created some of the most beautiful and accurate anatomical models of her time. She came from a Bologna family of artists and scientists, her father being a painter and her mother a midwife. While a student at the University of Bologna, she became interested…
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Conflict about the clitoris: Colombo versus Fallopio
Howard FischerUppsala, Sweden “The truth is rarely pure and never simple.”– Oscar Wilde The clitoris, a female genital structure anatomically homologous to the penis, was known to the ancients. In 540 BC, the Greek Hipponax made one of the earliest references to it. It was not mentioned by Hippocrates,1 but Arabic, Persian, and Roman writers…
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The two Sylvius anatomists
Buried deep in the cobwebs of medical history lies the persisting misconception that a single person called Sylvius made important advances in the discipline of anatomy. But in fact, there were two persons remembered by that name. There was Jacobus, whose name is most commonly linked to the Aqueduct of Sylvius, and there was Franciscus,…
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Christopher Wren’s contributions to medicine
JMS PearceHull, England An extraordinary natural philosopher and Renaissance man, Christopher Wren (1632–1723) (Fig 1) was primarily an astronomer and architect.1 He is remembered mostly for his work after the Great Fire of London of 1666 as designer of St. Paul’s Cathedral, originally erected in AD 604. Wren laid the first stone at on Ludgate…
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From silks to science: The history of hematoxylin and eosin staining
Vidhi NaikAberdeen, Scotland Introduction Hematoxylin and eosin, dyes used to stain tissue samples, collectively known as H&E, form the benchmark for histological stains. These dyes possess a profound and alluring history, which includes stories of the fabric industry, pirates, fine art, and eventually histology. The development of hematoxylin The origins of hematoxylin can be traced…
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Diocles of Carystus
Diocles of Carystus (probably 375–300 BC), also known as Diocles Medicus, came from the island of Euboea but is remembered as a resident of Athens. He wrote on animal anatomy, dietetics, physiology, embryology, and medical botany, but only fragments of his writings survive. His work on anatomy may have been the first of its kind…