Hektoen International

A Journal of Medical Humanities

Tag: acromegaly

  • De l’acromegalie: Maladie de Pierre Marie

    JMS PearceHull, England Pierre Marie (1853–1940) described two patients in Charcot’s clinic who showed enlargement of the extremities and face, for which he proposed the term acro-megalie.1 He established and named acromegaly as distinct from other causes of somatic overgrowth. He also acknowledged Saucerotte’s unmistakable earlier account of 1801.2 Pierre Marie described the now classical…

  • The ordeal of Mary Ann Bevan

    Howard FischerUppsala, Sweden “May you be the proof that man can endure anything.” – Yiddish curse“Beauty vanishes; virtue is lasting.” – Johann Wolfgang von Goethe From the 1840s through the 1940s, “freak shows” were very popular in the western world, “a normal staple of American culture.”1 People were exhibited because of their appearances: “giants,” “dwarves,”…

  • Trijntje Keever—a tall tale

    Orit Pinhas-HamielHamiel UriTirosh AmitRamat Gan, Israel There is a life-size painting in the city of Edam in The Netherlands that portrays a girl who is exceptionally tall with disproportionately long hands. The artist is unknown, but the name of the girl in the picture is Trijntje Keever. Trijntje was born in April 1616, the daughter…

  • Harvey Cushing and pituitary diseases

    JMS PearceHull, England, UK Of the many aspects and contributions of Harvey Williams Cushing (1869-1939) (Fig 1), this sketch concentrates on his identification of a basophilic tumor of the pituitary with adrenal hyperfunction that he called pituitary basophilism1 (Fig 2). It is now known as Cushing’s disease. Symptoms caused by primary adrenal, iatrogenic, and ectopic…

  • John Hunter, Harvey Cushing, and acromegaly

    Kevin R. Loughlin Boston, Massachusetts, United States   Figure 1. Charles Byrne, a giant, George Cranstoun, a dwarf, and three other normal sized men. Etching by J. Kay, 1794. Credit: Wellcome Collection. (CC BY 4.0) Introduction John Hunter and Harvey Cushing were two of the most preeminent surgeons of their eras. John Hunter is considered…

  • Sergei Rachmaninoff: The dichotomy of life and music

    Michael YafiChaden YafiHouston, Texas, United States Sergei Rachmaninoff (1873-1943), a Russian composer, was known for having very large hands. With a span that covered twelve white keys on the keyboard (the interval of a thirteenth), he could play a left-hand chord of C, E flat, G, C, and G.1 This has led some medical experts…

  • Sergei Rachmaninov, the pianist with very big hands

    Sergei Rachmaninov, the famous Russian composer, pianist, and composer, was born in 1873 into a family that descended from the Moldavian prince Stephen the Great. At age four he began piano lessons and already displayed remarkable talent. He was sent to study music at the St. Petersburg Conservatory when ten years old, and, upon being…