Hektoen International

A Journal of Medical Humanities

Tag: tetanus

  • Koch’s postulates revisited

    JMS PearceHull, England Van Leeuwenhoek (1632–1722), a Dutch botanist, using his early microscope observed single-celled bacteria, which he reported to the Royal Society as animalcules. The science of bacteriology owes its origin to two scientists of coruscating originality, Louis Pasteur and Robert Koch. Pasteur may be described as master-architect and Koch as master-builder of the…

  • Caleb Hillier Parry MD FRS

    JMS PearceHull, England, United Kingdom Hyperthyroidism or exophthalmic goiter, often called Graves’ disease or Basedow’s disease, was first recorded by Caleb Parry (1755-1822) (Fig 1) posthumously in 1825. William Osler called the affliction “Parry’s disease.” Caleb Parry was born in Cirencester, the son of Joshua Parry, a dissenting Presbyterian minister. He attended Cirencester Grammar School…

  • How conflict and bureaucracy delayed the elimination of yellow fever

    Edward McSweeganKingston, Rhode Island, United States The Golden Age of Bacteriology (1876–1906) saw the emergence of techniques to cultivate bacterial pathogens and develop vaccines and anti-toxin therapies against them. The new bacteriologists rapidly identified the agents causing anthrax, gonorrhea, typhoid, tuberculosis, cholera, tetanus, diphtheria, plague, and other infectious diseases. One microbe that remained stubbornly elusive…