Tag: mutation
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“Am not I a fly like thee?” Drosophila melanogaster and the human genome
Marshall A. Lichtman Rochester, New York, United States A fruit fly displaying its large red eye. Among Thomas Hunt Morgan’s many contribution to the burgeoning science of genetics, he observed some male fruit flies had a mutant white eye. By cross-breeding males with mutant white eyes with females with the dominant trait and, subsequently,…
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Early clinical and molecular discoveries in Long QT Syndrome
Göran WettrellSweden Sudden and unexpected death in people who are less than thirty-five years of age is associated with negative autopsy results in forty percent of cases.1 Long QT Syndrome (LQTS) is one of the most common cardiac ion channelopathies to cause sudden death in young people. In the late 1950s and early 1960s, reports…