Hektoen International

A Journal of Medical Humanities

Tag: Marshall A. Lichtman

  • “Am not I a fly like thee?” Drosophila melanogaster and the human genome

    Marshall A. LichtmanRochester, New York, United States Animal models have been essential to medical research for millennia. Ethical concerns about their use has led to a decrease in use of large animals (e.g., dogs, cats). Perhaps the smallest of research animals is Drosophila melanogaster, a fruit fly, one tenth inch in length, which has contributed…

  • Mitochondrial DNA: a maternal gift

    Marshall LichtmanRochester, New York, United States DNA is arrayed on twenty-three pairs of chromosomes in human cell nuclei. It is coiled tightly around proteins called histones that together with DNA form a chromosome. The largest chromosome carries several thousand genes and the smallest several hundred. DNA is so tightly wound that uncoiled from a single…

  • The first effective chemotherapy for cancer

    Marshall A. LichtmanRochester, New York, United States Sulfur mustard gas had no influence on the outcome of the battle at Ypres during World War I despite the many deaths and severe injuries it inflicted. Since then, chemical weapons have been used in conflicts at least fifteen times between 1919 and 2016—in the Iraq-Iran War, by…

  • Terminal digit preference

    Marshall Lichtman Rochester, New York, United States Numbers that end in zero motivate and energize people. Recall Y2K, when the world celebrated on January 1, 2000. The irresistibility of zeros resulted in everyone celebrating on the wrong date: the new millennium started on January 1, 2001, not 2000. The first year of the Julian calendar in…

  • Deserving but unrecognized: the forty-first seat

    Marshall A. LichtmanRochester, New York, United States The Nobel Prizes Each year on December 10th, the anniversary of Alfred Nobel’s death, the Nobel Foundation and the Swedish royal family recognize the individuals deemed to have made the greatest achievements in chemistry, physics, physiology or medicine, and literature; and the Norwegian Nobel Committee recognizes “the person…

  • Masters, Lindstrom, and decanal adventures

    Marshall A. LichtmanRochester, New York, USA One of the responsibilities of the dean is to foster the relationship of alumni with the school. This effort can lead to enhanced financial support, but it can also bind accomplished graduates, who may or may not think fondly of their alma mater, to the school and its programs.…