James R. Wright Jr. Calgary, Alberta, Canada   JJR Macleod circa 1928. Credit: University of Toronto. Via Wikimedia. In 1921, Fred Banting and Charley Best, working under the supervision of JJR Macleod, made crude pancreatic extracts from duct-ligated dog, fetal bovine, or whole adult bovine pancreata and used these to treat diabetes in depancreatized dogs.…