Wilson EngelGilbert, Arizona, United States Perhaps the best known and least forgettable of all Renaissance art works depicting the graphic effects of disease is Matthias Grünewald’s Isenheim Altarpiece (1506–1515), now in the Musée d’Unterlinden, Colmar.1 On the closed center portion of the altarpiece, is Grünewald’s famous portrayal of the Crucifixion in which the intensely human…