Hektoen International

A Journal of Medical Humanities

Tag: circadian rhythms

  • A note on circadian clocks

    JMS PearceHull, England I first started to enquire about circadian rhythms when wondering what it was that caused the periodicity of migraines in relationship to such diverse factors as emotions, tiredness, relaxation, hormonal changes, bright lights, and noise.1 The periodic threshold appeared susceptible to hypothalamic function, which in turn was modulated by seasonal patterns and…

  • “Am not I a fly like thee?” Drosophila melanogaster and the human genome

    Marshall A. LichtmanRochester, New York, United States Animal models have been essential to medical research for millennia. Ethical concerns about their use has led to a decrease in use of large animals (e.g., dogs, cats). Perhaps the smallest of research animals is Drosophila melanogaster, a fruit fly, one tenth inch in length, which has contributed…