Hektoen International

A Journal of Medical Humanities

Tag: chromosomes

  • Gregor Johann Mendel, father of modern genetics (1822–1884)

    Gregor Mendel was an Austrian scientist and Augustinian friar who laid the foundation of the science of heredity and genetics. Although his contributions to science were not widely recognized during his life, his work with pea plants in the mid-19th century revolutionized our understanding of how traits are inherited across generations, thus greatly influencing medicine,…

  • “Can you define the word ‘woman’?”

    Jayant RadhakrishnanDarien, Illinois, United States “The more you know the more you realize you don’t know.”— Aristotle (384 BCE-322 BCE) On March 22, 2022, a US senator asked the nominee for Associate Justice of the United States Supreme Court: “Can you define the word woman?” The nominee replied, “I can’t.” The senator followed up with,…

  • Mitochondrial DNA: a maternal gift

    Marshall LichtmanRochester, New York, United States DNA is arrayed on twenty-three pairs of chromosomes in human cell nuclei. It is coiled tightly around proteins called histones that together with DNA form a chromosome. The largest chromosome carries several thousand genes and the smallest several hundred. DNA is so tightly wound that uncoiled from a single…

  • The first description of DNA: A six million dollar letter from Francis to Michael Crick

    Marshall A. Lichtman Rochester, New York, United States In the April 25, 1953 issue of the biomedical journal Nature, three articles were published on the structural characteristics of DNA. One was a three-dimensional model of DNA constructed by James Watson and Francis Crick of the Cavendish Laboratory, Cambridge University, who did no experiments to arrive at…