Benjamin Chin-YeeToronto, Ontario, Canada In the spring of 1953 at the Verdun Protestant Hospital in Montreal, the psychiatrist Heinz Lehmann initiated the first trial of chlorpromazine in North America, treating “psychomotor excitement” in patients with diagnoses ranging from manic depression to schizophrenia.1,2 Within weeks, the drug proved a remarkable success: patients’ delusions, hallucinations and thought…