Category: Infectious Disease
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Albert Alexander: Unsung hero of penicillin
JMS PearceHull, England Hartnup disease, Christmas disease, and Lou Gehrig’s disease are instances of the rare naming of diseases after the patients so afflicted. There are other medical discoveries, disorders, or treatments in which the crucial part played by the patient is unattributed. One example relates to the early days of penicillin. The story of…
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Kuru, the laughing disease of New Guinea
New Guinea is the second-largest island in the world that is not a continent (after Greenland). It is divided into the Republic of Papua-New Guinea in the east and a western area that belongs to Indonesia. In both parts, indigenous populations face significant health challenges because of poverty, parasitic diseases, and poor medical facilities. Of…
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Onchocerciasis, a continuing cause of blindness
Among the various illnesses that deprive humans of their sight, onchocerciasis ranks highest. It affects millions of people in sub-Saharan Africa, as well as substantial numbers in Yemen and isolated areas of Brazil and Venezuela. Transmitted by infected blackflies that breed near fast-flowing streams and rivers, it is commonly known as “river blindness.” The disease…
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Sand flies, leishmaniasis, and kala-azar
Sand flies are about three millimeters long and gray, brownish or golden, with long, piercing mouthparts adapted for sucking blood from their hosts. These seemingly innocuous creatures, classified as belonging to the genus Phlebotomus or Lutzomyia, have long legs and hairy wings held in a vertical V-shape when at rest. They seek moist resting places…
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Trachoma: Contained but not yet subdued
Trachoma is a chronic eye infection caused by Chlamydia trachomatis, a bacterium at first thought to be a virus because of its minuscule size. It is the most common infectious cause of blindness worldwide, striking repeatedly in early childhood and, until recently, blinding millions.1 In 1907, Ludwig Halberstadter and Stanislaus von Prowazek observed the causative…
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Echinococcus granulosus, the sheepdog worm
In the days when Britain ruled the waves and its colonies, some sheep from Thomas Hardy’s Wessex and other counties followed their masters to the antipodes instead of stupidly jumping off a cliff.1 They multiplied in the sun and produced much wool, some of which was later returned to England under the imperial preference system…
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Filariasis and elephantiasis, plagues of the tropics
Imagine being bitten by a mosquito, not in your hometown but in one of the countries you have always longed to visit. After a few days, you may not feel well. This is because you have been invaded by the tiny micro-larvae offspring of a worm that lives in another person. You may or may…
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Rabies, still a deadly disease
The man recovered of the bite,The dog it was that died!—Oliver Goldsmith Unfortunately, this is untrue! An estimated 60,000 people die each year from rabies and most cases are due to dog bites. Rabies affects largely the poor rural populations of Africa and Asia, in India, Pakistan and Bangladesh, in Sri Lanka and Thailand, the…
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“Satturday” by Lady Mary Wortley Montagu, who helped introduce smallpox inoculation to England
Cristóbal Berry-CabánFort Liberty, North Carolina, United States Lady Mary Wortley Montagu1 was born in 1689 to an aristocratic family. She was highly intelligent and self-educated by having access to her father’s library, studying the classics, and even learning Latin. In 1712 she rejected her father’s choice and eloped with Edward Wortley Montagu, a young Whig…
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Mumps: Dolor et tumor
Mumps usually occurs in outbreaks, most often between the ages of 5–9, usually in the winter and spring in temperate climates but at any time in the tropics. After infecting the upper respiratory tract, this contagious virus spreads to the salivary glands, the lymph nodes, the blood, and throughout the body. Symptoms at first are…