Hektoen International

A Journal of Medical Humanities

Author: Hektoen International

  • The enigma of mass psychogenic phenomena

    Umut AkovaAtlanta, Georgia, United States In the stifling heat of 1518, Strasbourg, France was gripped by a bizarre spectacle: a mass outbreak of uncontrollable dancing. In the city’s streets, men, women, and children danced wildly, their movements frantic and seemingly without purpose. Despite efforts to stop the madness, the frenzy continued unabated, with fear and…

  • Hendrick Goltzius (1558–1617): The artist’s hand

    James L. FranklinChicago, Illinois, United States In 1588, when Hendrick Goltzius created this striking drawing (Fig. 1) of his deformed right hand, the thirty-year old Haarlem draftsman and engraver was already one of the most influential, well-recognized artists in Europe. In a sense, the drawing was his signature writ large, as evidenced in an anecdote…

  • Byzantine Emperor John Tzimisces: Murder, charity, & leprosy

    Sally MetzlerChicago, Illinois, United States Few historical figures present singular profiles of good or evil. Often, the confluence of disparate actions molds the fame or infamy of great leaders. A prime example is Byzantine Emperor John Tzimisces (b. 925–d. 976). Though he rose to power through murder, he consistently displayed a marked benevolence towards the…

  • It was the best of times, it was the worst of times

    It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, it was the season of light, it was the season of darkness, it was the spring of hope, it…

  • Dr. William Hall and rickets

    JMS PearceHull, England Today, few Western doctors have seen children suffering from rickets, an extremely common crippling scourge of children recorded since the second century AD. Whistler, Boot, and Glisson in the seventeenth century described the clinical features. Its cause was a mystery. In a letter written around 1664, Sir Thomas Browne (1605–1682) describing rooks/crows,…

  • Nurse Helen Repa takes charge in a disaster

    Howard FischerUppsala, Sweden “It would not be possible to praise nurses too highly.”– Stephen Ambrose, American historian On July 24, 1915, the Western Electric Company, a technology and engineering giant, had arranged an excursion and picnic for several thousand of its employees. Five Great Lakes excursion boats had been chartered to take them to a…

  • Salvador Luria and the bacteriophage

    Philip LiebsonChicago, Illinois, United States In 1859, the French naturalist Jean-Baptiste Lamarck proposed that if an organism is changed by environmental stimuli, these changes would be passed on to offspring. This theory was eventually disproven. One important study disproving this concept led to the Nobel Prize in Physiology or Medicine for Salvador Luria, Max Delbrück,…

  • Rembrandt: Tobias Healing His Father’s Blindness

    James L. FranklinChicago, Illinois, United States Rembrandt Harmenszoon van Rijn’s Tobias Healing his Father’s Blindness, painted in 1636, depicts the climactic moment in the Book of Tobit when Tobias returns to his father’s home and instills the gall (bile) he had taken from a giant fish into his blind father’s eyes, thereby restoring his sight.1…

  • The discovery of heparin

    Mostafa ElbabaDoha, Qatar The sulfated glycosaminoglycan known as heparin is the most common anticoagulant used in clinical medicine. Its therapeutic role is to increase antithrombin activity. While its physiologic role in humans is not fully understood, heparin is stored and secreted from mast cells at sites of tissue injury and is believed to provide local…

  • Propagating penicillin in Peoria: From discovery to mass production

    Julius BonelloMichael NeffZoe DemkoPeoria, Illinois, United States One of the greatest medical achievements of the twenty-first century was the creation of penicillin. The road to this great achievement began almost 300 years ago when Antonie van Leeuwenhoek (1632–1723), a draper by trade who had no science background, wished to assess the quality of his threads.…