Hektoen International

A Journal of Medical Humanities

Year: 2026

  • A second mind in scientific writing

    Rao UppuBaton Rouge, Louisiana, United States Clarity in scientific writing is a rare achievement. As Margaret Thatcher would have said in a different context, it does not fall from Heaven but needs work, often a lot of it. I learned this years ago, not in a laboratory or a seminar, but in my living room,…

  • “These late eclipses … portend no good to us” – Shakespeare

    Edward TaborBethesda, Maryland, United States Introduction Eclipses of the sun or moon were powerful images used by William Shakespeare in ten of his plays and poems.1 Shakespeare’s characters believed that eclipses were under the control of evil forces, that eclipses could predict the fall of governments, and noted how people blamed their weaknesses and failures…

  • The rise and fall of railway spine

    Lenny GrantSyracuse, New York, United States By 1864, British railways were responsible for 36 deaths and 700 injuries annually.1,2 Yet the most perplexing cases were not the visibly wounded, but those passengers who walked away apparently unharmed, only to develop debilitating symptoms days or weeks later. These survivors experienced what the Lancet described as “disturbed and diminished…

  • A Polish tragedy and a case without a diagnosis

    On the morning of September 1, 1939, German troops attacked Poland without a declaration of war. Two weeks later, on September 17, while Poland was defending itself in the west, the Soviet Union attacked from the east. This two-pronged attack was too much for Poland to handle. On October 6, 1939, its last troops surrendered.…

  • Nicolaas Fontanus, eminent Dutch physician

    Annabelle SlingerlandLeiden, Netherlands In the seven provinces of the Dutch Republic, freedom of thought and inquiry thrived in the seventeenth century. The University of Leyden, founded in 1575, embraced medicine and botany, and nurtured literature, poetry, and theatre. It was against this cultural backdrop that Nicolaas Fontanus (Fonteyn) worked as a physician, playwright, and poet.…

  • Chlorosis, the green anemia of young women

    Chlorosis was one of the most common diseases affecting adolescent girls and young women in Europe and North America during the 17th to 19th centuries. Its main features were a pale or greenish appearance, fatigue and weakness, shortness of breath, palpitations, loss of appetite, and amenorrhea or irregular menstruation. Fanny Price in Mansfield Park, Madame…

  • Martinus van Marum, physician, scientist, and inventor

    Annabelle SlingerlandLeiden, Netherlands Martinus van Marum, who was born in 1750 during the era of the Republic of the Seven United Netherlands, went on to enjoy a remarkable career in science. His father, Petrus van Marum, was a graduate engineer from Groningen who had started a pottery-factory in Delft, married Cornelia van Oudheusden, and had…

  • Eggplants: History and science

    The eggplant belongs to the genus Solanum of the nightshade family Solanaceae, along with the tomato and potato. Botanically it is a fruit, specifically a berry, though it is treated like a vegetable in the kitchen. Also belonging to the Solanum genus are chili peppers, as well as the poisonous Atropa belladonna and Datura stramonium (jimson weed).…

  • Johannes Lange of Heidelberg

    Johannes Lange of Heidelberg is sometimes credited with being the first to describe what later became known as “chlorosis” but that he called morbus virgineus, the disease of virgins. Born in Silesia in 1485, Lange went to study philosophy at the University of Leipzig, but later found he was more drawn to medicine and migrated…

  • The silence of Dona Zefa

    Guilherme CoelhoSão Paulo, Brazil Josefa Maria do Carmo—Dona Zefa to everyone—was the kind of woman you knew before you met her. The whole favela spoke of her like a patron saint: with respect, affection, and a reasonable fear of not wanting to disappoint her. Seventy-two years old, the widow of Seu Agenor, she was mother…