Hektoen International

A Journal of Medical Humanities

Tag: Alexander Fleming

  • Propagating penicillin in Peoria: From discovery to mass production

    Julius BonelloMichael NeffZoe DemkoPeoria, Illinois, United States One of the greatest medical achievements of the twenty-first century was the creation of penicillin. The road to this great achievement began almost 300 years ago when Antonie van Leeuwenhoek (1632–1723), a draper by trade who had no science background, wished to assess the quality of his threads.…

  • Recognition at last

    Jayant Radhakrishnan Darien, Illinois, United States Andrew Moyer, in his Peoria laboratory, discovered the process for mass producing penicillin. USDA-ARS National Center for Agricultural Utilization Research. Public domain.    “Though she be but little, she is fierce.”  — William Shakespeare, A Midsummer Night’s Dream     The adage “out of sight, out of mind” appears to…

  • Serendipity in science and medicine

    JMS Pearce Hull, England, United Kingdom   Photo by Tyler Merbler on Flickr. CC BY 2.0. The most exciting phrase to hear in science, the one that heralds new discoveries, is not “Eureka!”, but “That’s funny…” – Isaac Asimov   Horace Walpole (son of the first British Prime Minister, Sir Robert Walpole) coined the word…

  • Nobel Laureate Surgeons

    Jayant Radhakrishnan Darien, Illinois, United States Mohammad Ezzi Jizan, Saudi Arabia   Originally published in the World Journal of Surgery and Surgical Research 2020; 3: 1206 under a Creative Commons Attribution License. Republished with author permission.   Introduction The Nobel Prize for physiology or medicine has been awarded to 219 scientists in the last 119…

  • Sir Alexander Fleming: A microbiologist at work and play

    Jayant Radhakrishnan Darien, Illinois, United States   “Seemingly Simple Elegance” by Arwa Hadid. American Society for Microbiology Agar Art 2019 Professional. Undergraduate MLS student, Oakland University, Rochester Hills, MI, United States i Sir Alexander Fleming had many talents. His discoveries of lysozyme in 1923 and in 1928 the antibiotic effect of the fungus Penicillium notatum are…

  • St. Mary’s Hospital, birthplace of penicillin

    Anabelle S. Slingerland Leiden, Netherlands Kevin Brown London, England     Lithograph of St. Mary’s Hospital, 1853 On April 23, 2018, Prince William and the Duchess of Cambridge left the Lindo Wing of St. Mary’s Hospital in London with their new baby boy. Fans of the Royals, who had been camping outside St. Mary’s for…

  • Chance in the origins of antibiotics

    William Kingston Dublin, Ireland   The discovery of antibiotics has been described as the “domestication of microorganisms” and ranks in importance with the domestication of animals as part of settled agriculture about 10,000 years ago. It depends upon antagonism between bacteria, which had been noticed as early as 1874, and Pasteur commented then that if…

  • Looking back 175 years

    Biji T. KurienOklahoma, USA It was a time when surgery was performed in the raw. Obviously a horrendous nightmare for both patient and surgeon, it was performed only in do-or-die situations. The odor of pus in various stages of decomposition pervaded hospitals. Deaths from various diseases and surgery were common. Treatment of ailments with mercury…