Category: Infectious Disease
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Martinus Beijerinck: A co-discoverer of viruses
Philip LiebsonChicago, Illinois, United States As early as 1676, Dutch textile worker Anthony Van Leeuwenhoek, working with an early microscope, was the first to identify bacteria. Because of the size of bacteria, easily seen by a microscope, it was inevitable that bacteria would be discovered by someone. Not so with viruses. Although the smallest bacteria…
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Salvador Luria and the bacteriophage
Philip LiebsonChicago, Illinois, United States In 1859, the French naturalist Jean-Baptiste Lamarck proposed that if an organism is changed by environmental stimuli, these changes would be passed on to offspring. This theory was eventually disproven. One important study disproving this concept led to the Nobel Prize in Physiology or Medicine for Salvador Luria, Max Delbrück,…
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Propagating penicillin in Peoria: From discovery to mass production
Julius BonelloMichael NeffZoe DemkoPeoria, Illinois, United States One of the greatest medical achievements of the twenty-first century was the creation of penicillin. The road to this great achievement began almost 300 years ago when Antonie van Leeuwenhoek (1632–1723), a draper by trade who had no science background, wished to assess the quality of his threads.…
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Epidemics: The deadly foes of humanity
There was a time when humans may have solely attributed their illnesses to powers that could turn rivers into blood, kill firstborns, unleash swarms of frogs, lice, flies, and locusts (Exodus 7-10), cause contagious skin diseases (Leviticus 13:2-33), or send hideous, dangerous serpents to kill evildoers (Numbers 21:5-9).1 But in the relatively brief time of…
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Encephalitis lethargica: The sweating sickness of the 1920s?
Philip LiebsonChicago, Illinois, United States Epidemics may come and go, magically disappear, and sometimes recur. An example of this was the “sweating sickness” of sixteenth century Europe. Another example closer to our time was encephalitis lethargica, occurring as an epidemic in the late 1910s and early 1920s followed by only sporadic cases. Sporadic cases of…
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Measles again
JMS PearceHull, England “Measles is tearing through the UK, spooking health chiefs and parents alike.”– Daily Mail, 25 Jan 2024 Measles is notoriously infectious. Ninety percent of people exposed to an infected person will contract the disease. In many countries, because of misguided anti-vaccine activists, Measles Mumps Rubella (MMR) vaccination rates have fallen in recent…
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The final illness of Thomas Wolfe
Thomas Clayton Wolfe was one of the most important American novelists and short story writers of the early 20th century. When he died as a young man in 1938, he joined the long list of literati victims of the dreaded “captain of these men of death”—John Keats, Percy Shelley, Elizabeth Barrett Browning, Robert Louis Stevenson,…
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The seventeenth-century plague doctor’s hazmat suit
Howard FischerUppsala, Sweden “There are plagues, and there are victims, and it is the duty of good men not to join forces with the plagues.”– Albert Camus, The Plague The plague (later called “the black death”) reached Europe from eastern Russia in 1346. By the time the epidemic ended in 1352, one-third of Europe’s population…
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Sporozoites: The elusive assassins
Jayant RadhakrishnanChicago, Illinois, United States Almost 5,000 years ago, the Chinese described a disease that presented with intermittent fevers, enlarged spleens, and a predilection to epidemics. Those malarial infections were possibly caused by Plasmodium vivax (P. vivax) since P. malariae is unlikely to cause epidemics. The Chinese did not mention mortality following these symptoms; therefore,…